What is a Migraine?

A migraine is an intense, throbbing, typically one-sided headache. It often includes nausea, vomiting, sensitivity to light, and sensitivity to sound. The pain and symptoms from a migraine headache may be worse than the pain and symptoms of a common headache.
Migraines affect about 12% of Americans. Occurring three times more often in women than in men, migraines are most common in individuals between 30 and 39 years old. However, adolescents can also experience migraines.

What does a migraine feel like?

A migraine is an intense, throbbing, headache that typically occurs on one side. Along with the pain of the headache, other symptoms often include nausea, vomiting, and sensitivity to light and sound. However, before a migraine headache actually begins, some people have visual symptoms, which can include seeing what looks like flashing lights or wavy lines, which are called an “aura.”

How long does a migraine headache last?

Migraine headaches typically last for hours. They can also last for more than a day, but that’s rare.

Do migraines occur just once or can they come again?

Unfortunately, migraines can return often, although the strength and frequency of attacks may vary.

How do I know I have, or if my teen has, a migraine?

You shouldn’t try to diagnose yourself or your teenager when it comes to migraines. It’s important for you to consult a physician, who will review symptoms and determine whether a migraine is the correct diagnosis.

INDICATION

*AXERT® tablets are indicated for the acute treatment of migraine with or without aura in adults. AXERT® tablets are indicated for the acute treatment of migraine headache pain in adolescents age 12 to 17 years with a history of migraine attacks with or without aura usually lasting 4 hours or more (when untreated). In adolescents age 12-17 years, efficacy of AXERT® on migraine associated symptoms (nausea, photophobia and phonophobia) was not established.

Important Limitations

AXERT® should only be used where a clear diagnosis of migraine has been established. If a patient has no response for the first migraine attack treated with AXERT®, the diagnosis of migraine should be reconsidered before AXERT® is administered to treat any subsequent attacks. In adolescents age 12 to 17 years, efficacy of AXERT® on migraine-associated symptoms (nausea, photophobia, and phonophobia) was not established. AXERT® is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine. Safety and effectiveness of AXERT® have not been established for cluster headache which is present in an older, predominantly male population.

Important Safety Information

AXERT® is a prescription medication for the acute treatment of migraine with or without aura in adults, and for the acute treatment of migraine headache pain in adolescents age 12 to 17 years with a history of migraine attacks with or without aura usually lasting 4 hours or more (when untreated). If you have no response for the first migraine attack treated with AXERT®, then your doctor will need to see if you really have migraine before you take AXERT® to treat any future attacks. You should not take AXERT® if you have heart disease, uncontrolled high blood pressure or have ever had heart disease. If you have risk factors for heart disease (high blood pressure, high cholesterol, diabetes, obesity, smoking, family history of heart attack, menopause, or are a male over 40 years of age), or if you are pregnant, nursing, or thinking about becoming pregnant, talk with your doctor before taking AXERT®. You should also tell your doctor if you have had a stroke of any type or any transient ischemic attacks, or if you have circulation (blood flow) problems, as you should not use AXERT®. Contact your doctor immediately if you are experiencing symptoms of pain, tightness, pressure, or heaviness in your chest, throat, neck, or jaw, shortness of breath, weakness, or slurring of speech, if you experience abdominal pain or bloody diarrhea, or if your fingers or toes become cold or discolored. In very rare cases, serious heart problems have occurred in patients without known heart disease.

AXERT®, like other triptans, may be associated with a potentially life-threatening condition mainly when taken together with selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), two classes of drugs for depression or other disorders. Common SSRIs are Celexa® (citalopram HBr), Lexapro® (escitalopram oxalate), Paxil® (paroxetine), Prozac®/Sarafem® (fluoxetine), Symbyax® (olanzapine/fluoxetine), Zoloft® (sertraline), and Luvox® (fluvoxamine). Common SNRIs are Cymbalta® (duloxetine) and Effexor® (venlafaxine). If you experience symptoms such as confusion, sweating, flushing, rapid heartbeat, diarrhea, muscle weakness, poor balance, or worsening headache, contact your doctor immediately.

Some people who take migraine medicines, like AXERT®, for 10 or more days every month may have worse headaches (medication overuse headache). If your headaches get worse, your healthcare professional may decide to stop your treatment with AXERT®.

Tell your doctor about all prescription and over-the-counter medications you are taking. Do not take AXERT® if you have taken an ergotamine-containing or ergot-type medication or another triptan in the last 24 hours. Do not take if you have had an allergic reaction to AXERT® or any of its ingredients. Tell your doctor if you have had an allergic reaction to a sulfonamide drug or if you are taking ketoconazole.

The most common AXERT® side effects in adults are nausea, sleepiness, tingling sensation, headache, and dry mouth.
The most common AXERT® side effects in adolescents are dizziness, sleepiness, headache, tingling sensation, nausea and vomiting.

Ask your doctor about side effects, possible drug interactions, and any other important questions you may have before taking AXERT®.

Celexa and Lexapro are registered trademarks of Forest Laboratories. Paxil is a registered trademark of GlaxoSmithKline. Symbyax, Prozac/Sarafem and Cymbalta are registered trademarks of Eli Lilly. Zoloft is a registered trademark of Pfizer. Luvox is a registered trademark of Solvay. Effexor is a registered trademark of Wyeth.

You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For full U.S. Prescribing Information, click here.

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This page was last modified on October 28 2015 at 09:20:50 EST.